Once I heard a bit of advice spoken by one adolescent boy to another. “Do you want to know if a girl likes you? Tell a really stupid joke, the stupider the better. If she laughs, she likes you.” It has been obvious for eons that laughter has a sexual side. I am not referring to sex as the subject of humor, but the differences in the way that people of different genders perceive what is funny and how they respond with laughter.

Allan Reiss and colleagues of Stanford University studied the response of male and female brains when reading comics. To a large degree they used similar parts of the brain–the part that makes sense of semantics and juxtaposition of ideas. The difference is brain function between genders existed but barely. It was not possible to tell who was male or female by viewing the response results. The part of brain that deals with executive…